Advances in Treating Metastatic Bone Cancer
First Cambridge Conference
October 2005
Advances in Treating Metastatic Bone Cancer: Summary Statement for the First Cambridge Conference
Allan Lipton, James R. Berenson, Jean-Jacques Body, Brendan F. Boyce, Oyvind S. Bruland, Michael A. Carducci, Charles S. Cleeland, Denis R. Clohisy, Robert E. Coleman, Richard J. Cook, Theresa A. Guise, Roger N. Pearse, Trevor J. Powles, Michael J. Rogers, G. David Roodman, Matthew R. Smith, Larry J. Suva, Robert L. Vessella, Katherine N. Weilbaecher, Laura King
Basic Mechanisms Responsible for Osteolytic and Osteoblastic Bone Metastases
Theresa A. Guise, Khalid S. Mohammad, Gregory Clines, Elizabeth G. Stebbins , Darren H. Wong, Linda S. Higgins, Robert Vessella, Eva Corey, Susan Padalecki, Larry Suva, John M. Chirgwin
Genomics and Proteomics of Bone Cancer
Aaron G. Marguiles, V. Suzanne Klimberg, Sudeepa Bhattacharrya, Dana Gaddy, Larry J. Suva
Molecular Mechanisms of Action of Bisphosphonates: Current Status
Fraser P. Coxon, Keith Thompson, Sharon Gordon & Michael J. Rogers
Biology of Bone Cancer Pain
Michael J. Goblirsch, Pawel P. Zwolak, Denis R. Clohisy
The Measurement of Pain From Metastatic Bone Disease: Capturing the Patient’s Experience
Charles S. Cleeland
Clinical Features of Metastatic Bone Disease and Risk of Skeletal Morbidity
Robert E. Coleman
High-linear Energy-transfer Irradiation Targeted to Skeletal Metastases by the Alpha Emitter 223Ra: Adjuvant or alternative to conventional modalities?
Øyvind S. Bruland, Sten Nilsson, Darrell R. Fisher, Roy H. Larsen
Breast Cancer: Bisphosphonate Therapy for Metastatic Bone Disease
Jean-Jacques Body
Multistate Analysis of Skeletal Events in Patients With Bone Metastases
Richard J. Cook, Pierre Major
New Potential Targets for Treating Myeloma Bone Disease
G. David Roodman
Wnt Antagonism in Multiple Myeloma: A Potential Cause of Uncoupled Bone Remodeling
Roger N. Pearse
Treatment for Myeloma Bone Disease
Howard S. Yeh, James R. Berenson
Targeting Factors Involved in Bone Remodeling as Treatment Strategies in Prostate Cancer Bone Metastasis
Robert L Vessella and Eva Corey
Src Inhibitors in Metastatic Bone Disease
Brendan F. Boyce, Lianping Xing, Zhenqiang Yao, Teruhito Yamashita, William C. Shakespeare, Yihan Wang, Chester A. Metcalf III, Raji Sundaramoorthi, David C. Dalgarno, John D. Iuliucci, Tomi K. Sawyer
Targeting Bone Metastasis in Prostate Cancer With Endothelin Receptor Antagonists
Michael A. Carducci and Antonio Jimeno
Oral Bisphosphonates as Adjuvant Therapy for Operable Breast Cancer
Trevor Powles, Alexander Paterson
Future Treatment of Bone Metastases
Allan Lipton
Skeletal Complications of Breast Cancer Therapies
Angela Hirbe, Elizabeth Morgan, Özge Uluçkan, and Katherine Weilbaecher
Treatment-Related Osteoporosis in Men With Prostate Cancer
Matthew R. Smith
